Research-led HealthTech in development

Multimodal intelligence for more informed anxiety care

Synapsona is developing a clinician-facing decision-support approach that brings clinical, cognitive, personality and neurophysiological information into one interpretable patient profile

Validation stage · Clinician in the loop · Privacy by design

The challenge

Complex treatment decisions are still built from fragmented information

Anxiety care can involve symptoms, cognitive functioning, personality-related patterns and neurophysiological signals. These sources are often assessed separately, making it difficult to form one coherent and clinically actionable view

Limited longitudinal view

Symptom change alone may not capture the full cognitive and functional picture over time

Unclear treatment pathways

Clinicians need evidence that helps structure when CBT, cognitive rehabilitation or a combined pathway should be considered

Fragmented assessment

Relevant information may sit across questionnaires, cognitive tools and specialist reports

Our approach

One interpretable profile across four evidence domains

The proposed platform is designed to organise complementary information without replacing clinical judgement

Neurophysiology

QEEG-derived features explored for their incremental value beyond simpler measures

Personality

Clinically relevant dimensions that may influence treatment engagement and response

Cognitive

Attention, working memory, inhibition and processing-related performance

Clinical

Validated symptom and treatment-outcome measures

From multimodal assessment to a clearer clinical conversation

Monitor

Track relevant clinical and cognitive change over time under professional supervision

Interpret

Present patterns, uncertainty and limitations in a clinician-facing view

Integrate

Bring the available signals into a quality-controlled multimodal profile

Assess

Collect structured clinical, cognitive, personality and eligible neurophysiological inputs

Initial focus

A focused research-to-clinic pathway for GAD

The first development programme focuses on Generalized Anxiety Disorder. The aim is to investigate whether a structured multimodal profile can support research and future clinical decision-making around CBT, computerised cognitive rehabilitation and combined pathways

  The proposed system is in development and has not yet been independently validated for clinical treatment selection

Research foundation

Built from a completed randomised four-arm intervention study

The concept originates from prospectively collected data from 60 adults across CBT, computerised cognitive rehabilitation, combined intervention and waiting-list control conditions. The research includes clinical outcomes and multimodal assessment data that can support carefully controlled secondary analyses and future hypothesis generation

This dataset is a proof-of-concept and feasibility asset. It is not presented as sufficient evidence for a generalisable clinical prediction system

Why the Netherlands

A strong environment for responsible clinical validation

The Netherlands offers a connected ecosystem across mental healthcare, clinical research, digital health and responsible AI. We aim to develop the next stage with Dutch academic and clinical partners, generate evidence in local practice, and build a GDPR-conscious and clinically usable workflow

What makes it measurable

Planned Dutch contribution

A defined validation partner, protocol and pilot milestones.

Clinical and academic collaboration

Transparent analyses, dissemination and reproducibility work.

Specialised knowledge creation

Human oversight, data governance and early regulatory planning.

Responsible product development

A Dutch-validated workflow designed for later adaptation to other EU settings.

European growth potential

Collaborate with us

Help shape a clinically useful validation programme

We are seeking conversations with Dutch GGZ providers, university researchers, neuropsychology and cognitive-rehabilitation specialists, QEEG and neurophysiology services, and advisers in medical software, data protection and clinical implementation.

Development roadmap

A staged path from research asset to clinically testable product

 

Indicative outputs

Focus

Stage

Use case, data and IP review, intended purpose, partner discovery

Scope, rights and design

1 Foundation 

Secure clinician-facing prototype, simple model baselines, usability testing

Workflow and model exploration

2 Prototype

Dutch feasibility study, prospective validation plan, risk and oversight documentation

Independent evidence

3 Validation

Clinical utility evidence, regulatory route, procurement and European expansion plan

Responsible implementation

4 Translation

 Frequently asked questions

 

Is Synapsona a diagnostic tool?


No. Synapsona is currently a research and development initiative. The proposed platform is intended to support qualified professionals and is not offered as a diagnostic service.


No. Human oversight and clinician interpretation are central to the proposed workflow.

QEEG is being explored as one potential information source. Its incremental value must be tested against simpler and less costly clinical models.


The project is at the validation and pre-MVP stage, supported by an existing research dataset and a defined development plan.


We welcome relevant conversations with Dutch clinical providers, universities, research groups and specialists in digital-health implementation, data governance and medical-software regulation.

Interested in responsible multimodal mental-health research?

We would value a conversation about clinical validation, research collaboration or responsible implementation in the Netherlands